Kawthar BOUCHEMAL's Home page
Kawthar BOUCHEMAL carries out multidisciplinary research activities in the field of biomaterials and nanotechnology for healthcare at the University of Paris Saclay since 2006. After a pharmacist graduate diploma, she completed a Master’s Degree in Medical and Biological Engineering and a PhD in Pharmaceutical Nanotechnology at the University of Claude Bernard Lyon-1 (2001-2003). She was post-doctoral fellow jointly at the University of Claude Bernard Lyon-1 and the University of Geneva in Switzerland. She has been appointed to the Institut Universitaire de France (IUF), an elite French institution, in recognition of her teaching and research activities (2015-2020).
Her research activities are focused on conception, characterization, and evaluation of the behaviors of morphology-controlled nanomaterials aiming to improve the efficacy and/or decrease the side effects of pharmaceutical drugs. Her work has led to novel environmentally responsive controlled release formulations and a series of bio- and mucoadhesive devices. Her research on self-associating polysaccharides and cyclodextrins has led to the development of new family of self-assembling anisotropic nanoparticles. Indeed, she serendipitously discovered that a simple mixing of an amphiphilic polysaccharide with alpha-cyclodextrin resulted in the formation of nano-objects that exhibited a typical hexagonal shape, flat surfaces and sharp edges. These particles exhibited intrinsic antimicrobial activities without drug addition.
Other research work deals with scaling-up the production of drug delivery systems. Kawthar Bouchemal performed a pioneer work on modelling and wall thickness estimation of polyamide nanocapsules. She demonstrated the existence of a power law relationship between nano-emulsion droplet size and turbulences created by emulsification and solvent diffusion process. Then, she demonstrated that this mathematical model is applicable for all processes for the production of colloidal nanocareers based on nanoprecipitation also called “ouzo effect”.
She serves in the editorial board of Pharmaceutical Research journal and was guest editor of the International Journal of Pharmaceutics. She was chair and/or member of the Organizing & Scientific committee of national and international meetings on Pharmaceutics & Biopharmaceutics.
In 2014, she co-founded a biotech company aiming to move her research from the laboratory to the clinic. She has been attributed the award for The Best Innovative Company by the French Minister of Higher Education and Research in 2013 and in 2016. She is founder and director a Master's degree program focused on the Protection and Management of Innovation in Health.
Université Paris Saclay - Faculté de Pharmacie
5 rue J-B Clément
92296 Châtenay-Malabry Cedex France
kawthar.bouchemal [a] universite-paris-saclay.fr