Kawthar BOUCHEMAL's Home page
Kawthar BOUCHEMAL carries out research activities in the field of bio-nanomaterials at the Institut Galien Paris Saclay (UMR University of Paris Saclay, CNRS 8612). After a Doctor of Pharmacy (PharmD) diploma, she completed a Master’s Degree in Medical and Biological Engineering and a PhD in Pharmaceutical Nanotechnology at the University of Lyon. She was supervised by Professor Hatem Fessi. Then, she was a post-doctoral fellow jointly at the University of Lyon and the University of Geneva. In 2015, she has been appointed to the Institut Universitaire de France, an elite French institution, in recognition of her teaching and research activities.
Her research activities are focused on conception, characterization, and evaluation of the behaviors of morphology-controlled nanomaterials aiming to improve the efficacy and/or decrease the side effects of pharmaceutical drugs. Her research on self-associating polysaccharides and cyclodextrins has led to the development of new family of self-assembling anisotropic nanoparticles. Indeed, she serendipitously discovered that a simple mixing of an amphiphilic polysaccharide with alpha-cyclodextrin resulted in the formation of nano-objects with a typical hexagonal shape, flat surfaces and sharp edges. These particles exhibited intrinsic antimicrobial and anti-inflammatory activities without drug addition. Other research work deals with process engineering applied for colloidal drug delivery systems. Kawthar Bouchemal performed a pioneer work on modelling of the kinetics of nanoparticle formation by interfacial polycondensation. She demonstrated the existence of a power law relationship between nano-emulsion droplet size and turbulences created by emulsification and solvent diffusion process. Then, she demonstrated that this mathematical model is applicable for the production of colloidal nanocareers based on nanoprecipitation (referred to as the Ouzo effect).
She serves in the editorial board of Pharmaceutical Research journal and was guest editor of the International Journal of Pharmaceutics. She was chair and/or member of the Organizing & Scientific committee of national and international meetings on Pharmaceutics & Biopharmaceutics.
Kawthar Bouchemal authored 79 publications and was inventor of 16 patents. In 2014, she co-founded a biotech company aiming to move her research from the laboratory to the clinic. She has been attributed the award for The Best Innovative Company by the French Minister of Higher Education and Research in 2013 and in 2016. She is founder and director a Master's degree program focused on the Protection and Management of Innovation in Health.